upstream fastcgi_backend {
    server 127.0.0.1:9000;
    server unix:/var/run/php5-fpm.sock;
    keepalive 10;
}
...
server {
  ...
  ...
  location ~ \.php {
    set $php_root /var/www/website/abc/public;
    include /etc/nginx/fastcgi_params;
 
    if ($request_uri ~ /(api/user/photos|api/user/posts) ) {
      set $php_root /var/www/website/rest/public;
    }
 
    if ($request_uri ~ /api/user/(photos|posts|links) ) {
      set $php_root /var/www/website/rest/public;
    }
 
    fastcgi_split_path_info ^(.+\.php)(/.+)$;
    fastcgi_param PATH_INFO $fastcgi_path_info;
    fastcgi_param PATH_TRANSLATED $php_root$fastcgi_path_info;
    fastcgi_param SCRIPT_NAME $fastcgi_script_name;
    fastcgi_param SCRIPT_FILENAME $php_root$fastcgi_script_name;
    fastcgi_pass fastcgi_backend;
    fastcgi_index index.php;
  }
  ...
}

upstream fastcgi_backend { server 127.0.0.1:9000; server unix:/var/run/php5-fpm.sock; keepalive 10; } ... server { ... ... location ~ \.php { set $php_root /var/www/website/abc/public; include /etc/nginx/fastcgi_params; if ($request_uri ~ /(api/user/photos|api/user/posts) ) { set $php_root /var/www/website/rest/public; } if ($request_uri ~ /api/user/(photos|posts|links) ) { set $php_root /var/www/website/rest/public; } fastcgi_split_path_info ^(.+\.php)(/.+)$; fastcgi_param PATH_INFO $fastcgi_path_info; fastcgi_param PATH_TRANSLATED $php_root$fastcgi_path_info; fastcgi_param SCRIPT_NAME $fastcgi_script_name; fastcgi_param SCRIPT_FILENAME $php_root$fastcgi_script_name; fastcgi_pass fastcgi_backend; fastcgi_index index.php; } ... }